- Community acquired pneumonia
- Lower respiratory tract infections
- Urinary tract infections
- Gonorrhoea
- Bacterial skin infections
- Ear and throat infections
Mechanism of action-
Amoxycillin inhibits the penicillin binding protein and thus inhibits the bacterial cell wall synthesis. this protein is responsible for crosslinking of D-alanine and D-aspartic acid.
Pharmacokinetics-
Absorption-
It is orally absorbed and is about 60% bioavailable
Protein Binding-
It is 17% bound to serum proteins
Metabolism-
It undergoes deamination, glucuronidation conjugation
Excretion-
It is excreted via urine
- Diarrhoea
- Stomach upset
- Skin rashes
- Headache
- Abnormal taste
- Vaginal yeast infections
- Contraindicated in people with known hypersensitivity
- Contraindicated in renal impairment
- Contraindicated in inflammatory bowel disease
- Ibuprofen
- Fluticasone nasal
- Zolpidem
- Atorvastatin
- Guaifenesin